Amiri Baraka (LeRoi Jones) Essay Example | Topics and Well Written Essays - 500 words

Amiri Baraka (LeRoi Jones) - Essay Example Even after retirement, he remained active and productive. The assassination of Malcolm X became the turning point of his life where he changed his name to Amiri Baraka and dissolved his marriage to Hettie Cohen. He became a leader of Newark’s African-American community. Amiri Baraka was well known for his writing. He used his popularity as a way of defending the weak from social injustices (Koolish, 2001). Through poems, plays, fiction, and essays, he showed his leadership by condemning oppression and racial injustice of the African American community in the United States (Epstein, 2006). Through his works and words, Baraka was able to he was able to promote drama created by African American playwrights and performed for the African American audience that showed African American issues (Baraka, 1995). For example, his two plays The Toilet and The Slave which were both written in the year 1962 showed his mistrust and hostility towards the white society. His award winning production, Dutchman, showed the damage that America inflicts on African men (Baraka, 2000). In 1960s racial discrimination against African Americans was still high. Many black leaders started to rethink their goals, while dome embraced more militant ideologies of self-defense and separatism (Lie, 2006). The struggle for civil rights was high aimed at drawing the attention of the nation to the brutality and injustice that African Americans faced. Even though the economic situation was good in the country, many blacks lived under poverty which was evident in many black urban neighborhoods. Leadership is the ability of a person to lead a group of people or a team to achieve specific task (Northouse, 2012). After studying Amiri Baraka, it is clear that leadership is an in built quality. It can also be attained through an individual’s experience which inspires the leader (OSullivan, 2009). Leadership cannot be learnt by simply reading about it but it is something that someone gets

A Growing “Threat” to Society Essay Example for Free

A Growing â€Å"Threat† to Society Essay The Internet is one of the most powerful sources of information today. Thus, it has the capacity to enlighten, as well as to mislead. This double-edged potential has turned the Internet into the latest avenue for terrorism. Terrorists are now harnessing the power of the Internet to wreak havoc among the public (Conway, 2002). Terrorists use the Internet mainly as a propaganda tool – it is a venue wherein they publicize their cause or explain their ideological justification without misinterpretation or censorship. As of 2002, a majority of the 33 groups deemed foreign terrorist organizations by the United States State Department had their own web sites. There are also many other websites, that, despite not being related to any terrorist group, provide information on how to commit terrorist activities such as bomb-making. The latter often escape criminal prosecution due to the First Amendment, which guarantees freedom of speech to the general populace (Conway, 2002). The very idea of cyber-terrorism, however, is not without contention. For one, it is still not clear as to what differentiates cyber-terrorism from freedom of expression. Also, there are certain Internet-related crimes that cannot be considered as cyber-terrorism, although they inflict damage upon the public. Indeed, terrorism in itself is already a notoriously difficult concept to define. The addition of computers to it further complicates the idea (Conway, 2002). The Internet: A New Weapon The Internet was originally intended as a means of resuming contact in the event of a nuclear attack. But due to its speed and convenience, it is currently a major venue for information, communication and commerce. As of September 2006, there were more than 1 billion Internet users worldwide (Vatis, 2006). With just one click of a mouse, an entrepreneur in Germany can deposit funds to a bank account in Switzerland and talk to a London-based cousin face to face through a web camera. A student in California, meanwhile, can learn everything about the Great Wall of China with merely a few keystrokes. After 9/11 It was only after 9/11 that the very concept of cyber-terrorism was actually developed. Before 9/11, Internet-related crimes were usually in the form of sending pornographic email to minors, defacing web pages, stealing credit card information and launching computer viruses (Conway, 2002). After 9/11, however, US officials realized that terrorist organizations could use the Internet to generate more bloodshed (Weimann, 2004). Al-Qaeda, for instance, could launch missiles or biological weapons to the US by simply pressing the â€Å"Enter† button of a laptop (Stohl, 2006). To a certain extent, the fears of the US were well-founded. In November 2000, an electronic attack was carried out from Pakistan against the Washington-based pro-Israeli lobbying group American Israel Public Affairs Committee (AIPAC). Aside from defacing AIPAC’s site with anti-Israeli commentaries, the attacker likewise stole some 3,500 email addresses and 700 credit card numbers, sent anti-Israeli diatribes to the addresses and published the credit card data on the Internet. The Pakistani hacker, known by the alias â€Å"Dr. Nuker,† claimed responsibility for the incident. It turned out that â€Å"Dr. Hacker† was a founder of the Pakistani Hackerz Club, an organization whose objective was to â€Å"hack for the injustice going around the globe, especially with (sic) Muslims† (Conway, 2002). The aforementioned cyber assault was not without precedent. The Lebanese Shiite Islamic group Hezbollah established its collection of web sites in 1995. At present, the group has three websites that can be viewed in either English or Arabic – one for its press office, another to describe its attacks on Israeli targets (http://www. moqawama. tv) and a third, Al-Manar TV, for news and information (http://www. manartv. com). These websites regularly provide the latest information about Hezbollah, including press statements, political declarations, photos, video and audio clips. An email address is also provided as contact information (Conway, 2002). After 9/11, as a result, federal agents issued subpoenas and search warrants to almost every major Internet-based company, including America Online, MSN, Yahoo! and Google. In addition, many web sites were subjected to official closure by the Federal Bureau of Investigation (FBI). Included among those that were closed down were radical Internet radio shows such as â€Å"IRA Radio,† â€Å"Al Lewis Live† and â€Å"Our Americas. † The â€Å"jihad web ring,† a collection of 55 jihad-related websites, lost dozens of its sites due to pullouts by Yahoo! Lycos Europe, meanwhile, created a 20-person team to filter its websites for illegal activity and terrorist-related content (Conway, 2002). Cyber-terrorism: Is There Really Such Thing? One of the most common arguments against cyber-terrorism is that it is an imaginary threat (Lacey, 2007). Contrary to popular perception, there is a minimal chance that cyber-terrorists would exact harm on innocent people by attacking corporate and governmental computer networks. As of this moment, terrorist organizations use the Internet only for fundraising, communications and propaganda. There is the possibility that terrorists might use computers as weaponry to a significant degree, but this will â€Å"probably happen in the (distant) future† (Conway, 2002). At present, terrorists would draw more attention to their cause by setting off bombs instead of hacking bytes (Conway, 2002). Instead of getting extremely paranoid about cyber-terrorism, the government should instead focus on eliminating cyber attacks against companies. As of July 2002, hackers had successfully launched at least 180,000 Internet attacks against more than 400 public, private, governmental and non-profit organizations. The brunt of these attacks fell on the power and energy industries, as well as on the technology and financial services. If left unchecked, these cyber attacks would be very detrimental to consumers – in order to make up for their losses to hackers, owners of the above-mentioned industries will have to raise the prices of their products and services (Fishman, Jospehberg, Linn, Pollack, Victoriano, 2002). Conclusion Paranoia over cyber-terrorism is very dangerous. Aside from diverting attention from more serious crimes such as cyber attacks, it violates civil rights and liberties. Under the guise of â€Å"fighting terrorism,† even websites whose only crime was to express radical ideas were closed down. While it is the duty of the state to safeguard its constituents from danger, doing so should not infringe their inalienable rights. It is true that terrorism might turn to cyberspace in the future in order to spread even more fear and bloodshed. But before the government rushes out to eliminate â€Å"cyber-terrorists,† it must first have a clear-cut concept of what constitutes cyber-terrorism and what makes a cyber-terrorist. Otherwise, the government will end up worse than the terrorists that it aims to get rid of. References Conway, M. (2002). What is Cyberterrorism? Current History, 101, 436-442. Retrieved October 17, 2008 from Academic Research Library. Fishman, R. M. , Josephberg, K. , Linn, J. , Pollack, J. , Victoriano, J. (2002). Threat of International Cyberterrorism on the Rise. Intellectual Property Technology Law Journal, 14, 23. Retrieved October 17, 2008, from ABI/INFORM Global. Lacey, D. ComputerWeekly. com. (2007, April 29). How Real is the Threat of Cyber Terrorism? Retrieved October 17, 2008, from http://www. computerweekly. com/blogs/david_lacey/2007/04/ how_real_is_the_threat_of_cybe. html Stohl, M. (2006). Cyber Terrorism: A Clear and Present Danger, the Sum of All Fears, Breaking Point or Patriot Games? Crime Law Soc Change, 46, 223-238. Retrieved October 17, 2008 from SpringerLink. Vatis, M. (2006). The Next Battlefield: The Reality of Virtual Threats. Harvard International Review, 28, 56-61. Retrieved October 17, 2008 from ABI/INFORM Global. Weimann, G. United States Institute of Peace. (2004, December). Cyberterrorism: How Real Is the Threat? Retrieved October 17, 2008, from http://www. usip. org/pubs/specialreports/sr119. html#threat

Inotropes, Vasopressors and Vasodilators

Inotropes, Vasopressors and Vasodilators Suruchi Hasija, Jatin Narula ,Vandana Maravi. ADRENERGIC RECEPTORS AND SIGNALING PATHWAYS The main control over cardiac contractility is provided by the ÃŽ ²Ã¢â‚¬â€œadrenergic signaling pathways and that over the vascular tone by both ÃŽ ±- and ÃŽ ²Ã¢â‚¬â€œadrenergic pathways. The ÃŽ ± and ÃŽ ² receptors are stimulated by catecholamines circulating in the bloodstream and those released locally from the adrenergic nerve endings. The two main subtypes of ÃŽ ²Ã¢â‚¬â€œadrenergic receptors (ÃŽ ²Ã¢â‚¬â€œARs) in the cardiovascular system are the ÃŽ ²1 and ÃŽ ²2 subtypes. Myocardial ÃŽ ²1 and ÃŽ ²2-AR stimulation leads to increased contractility, whereas vascular ÃŽ ²2-AR stimulation induces vascular smooth muscle relaxation. Drug binding to myocardial ÃŽ ²Ã¢â‚¬â€œARs activates stimulatory G protein. This leads to activation of the enzyme adenylate cyclase that catalyzes the conversion of ATP to cAMP. A cascade of intracellular reactions finally leads to the physiological effect of increased myocardial contraction or vasodilation. The ÃŽ ±Ã¢â‚¬â€œadrenergic receptors (ÃŽ ±Ã¢â‚¬â€œARs) are further classified as ÃŽ ±1 and ÃŽ ±2 subtypes. ÃŽ ±1-AR on vascular smooth muscles are the main mediators of vasoconstriction. ÃŽ ±2-AR on the neurons function in a negative feedback loop to control ÃŽ ±-adrenergic vasoconstriction. Stimulation of ÃŽ ±1-AR coupled to G protein activates phospholipase C which in turn raises intracellular Ca+2. Stimulation of ÃŽ ±2-AR coupled to inhibitory G protein inhibits adenylate cyclase, thereby lowering intracellular Ca+2. INOTROPES Inotropy or contractility is the intrinsic property of the cardiac myofibril. It defines the amount of work that the heart can perform at a given load. Contractility is primarily determined by the availability of intracellular calcium. Depolarization of the cardiac myofibril leads to the entry of a small amount of Ca+2 into the cell which triggers the release of additional Ca+2 from intracellular storage sites (sarcoplasmic reticulum). The binding of Ca+2 to troponin, displacement of tropomyosin from the binding site on actin and formation of actin-myosin crossbridges eventually leads to contraction of the myofibril. All inotropic agents act by increasing intracellular calcium. Catecholamines, phosphodiesterase inhibitors and calcium sensitizers are the broad classes of available inotropic agents. Catecholamines Catecholamines comprise the major type of available inotropic agents. Their chemical structure includes a catechol ring, catechol hydroxyl groups and variable side chains. Endogenous(present naturally in the body) catecholamines include epinephrine, norepinephrine and dopamine, and synthetic catecholamines include isoprenaline, dobutamine, dopexamine and fenoldopam. Besides acting directly on adrenergic receptors, some catecholamines may act indirectly by releasing or inhibiting reuptake of norepinephrine at the nerve terminal or by metabolism to form norepinephrine. Table 1: Site and mechanism of action of sympathomimetics Table 2: Haemodynamic effects of catecholamines and phosphodiesterase inhibitors CO=cardiac output, dp/dt=force of myocardial contraction(change in pressure/time), HR=heart rate, SVR=systemic vascular resistance, PVR=pulmonary vascular resistance, PCWP=pulmonary capillary wedge pressure, MVO2=myocardial oxygen consumption Modified from Lehmann A, Boldt J: New pharmacologic approaches for the perioperative treatment of ischemic cardiogenic shock. J Cardiothorac Vasc Anesth 19:97-108, 2005. Epinephrine Epinephrine, a naturally occurring catecholamine, is secreted from the adrenal medulla. The effects on ÃŽ ²Ã¢â‚¬â€œARs predominate at lower doses and on ÃŽ ±Ã¢â‚¬â€œARs at higher doses (> 0.1  µg/kg/min). It increases heart rate (HR), stroke volume (SV) and coronary blood flow (CBF). The rise in blood pressure (BP) results from increase in HR and cardiac output (CO). Systemic vascular resistance (SVR) decreases at low doses (ÃŽ ²2-AR effect) but increases at high doses (ÃŽ ± effect). It is metabolized in the liver by the enzymes catechol-O-methyl transferase (COMT) and monoamine oxidase (MAO), and the metabolites are excreted in urine. It has arrhythmogenic potential. In cardiac surgical patients it is used as an infusion at 0.01-0.4  µg/kg/min to wean patients with poor ventricular function off cardiopulmonary bypass (CPB). (Tables 1 and 2) Norepinephrine Norepinephrine is the postganglionic neurotransmitter in the sympathetic nervous system. It acts on ÃŽ ±1–AR, ÃŽ ±2–AR and ÃŽ ²1–AR, and has negligible action on ÃŽ ²2–AR. The ÃŽ ²1-AR action predominates at lower doses, thereby increasing inotropy, SV and CBF. It increases BP and SVR; but decreases HR. The CO remains unchanged. It has arrhythmogenic potential. The clinical dose range is 0.01 to 0.1  µg/kg/min. Like epinephrine, it is easily oxidized. It is metabolized by COMT and MAO and taken up by the sympathetic neurons. It decreases renal, hepatic, mesenteric and splanchnic blood flow. Dopamine Dopamine is a neurotransmitter in the central and peripheral nervous system. It is the immediate metabolic precursor of norepinephrine and epinephrine. It acts on ÃŽ ±Ã¢â‚¬â€œARs, ÃŽ ²Ã¢â‚¬â€œARs and dopaminergic receptors (DA1-DA5). At 0.5-3  µg/kg/min it increases renal and mesenteric blood flow (dopaminergic effects), between 3-8  µg/kg/min it increases HR and contractility (ÃŽ ²-AR effects) and, above 8  µg/kg/min it causes vasoconstriction (ÃŽ ±-AR effects). Intravenous dopamine does not cross the blood brain barrier. It is metabolized in the liver by COMT and MAO. Isoprenaline Isoprenaline has pure ÃŽ ²Ã¢â‚¬â€œAR agonist activity. It causes an increase in HR and contractility (ÃŽ ²1-AR effect) and decreases SVR (ÃŽ ²2-AR effect). CO increases due to combined ÃŽ ²1 and ÃŽ ²2-AR effect. It dilates pulmonary, skeletal, renal and mesenteric vascular beds. It is indicated in the treatment of pulmonary hypertension, bradycardia (especially after orthotopic heart transplantation), heart block and conduction abnormalities. It is used in the dose 0.01 to 0.1  µg/kg/min. it is metabolized in the liver by COMT. It is arrhythmogenic. Dobutamine Dobutamine is primarily a ÃŽ ²1-AR agonist and has positive inotropic effects. It causes modest increase in HR (ÃŽ ²2-AR effect) and decrease in SVR (ÃŽ ²2-AR effect). The clinical dose range varies from 2-15  µg/kg/min. It is particularly indicated in patients with myocardial pump failure. Its chemical structure lacks the hydroxyl group of catecholamines. It is metabolized in the liver, although not by COMT and MAO. It increases SV, CO and CBF. The arrhythmogenic potential is less than other catecholamines. Dopexamine Dopexamine is a synthetic analog of dopamine. It has potent ÃŽ ²2-AR and dopamine agonist properties and little ÃŽ ²1-AR and ÃŽ ±-AR activity. It causes vasodilation, increase in HR and inotropy. CO and renal blood flow are increased. It is used in the dose 1-10  µg/kg/min. It undergoes methylation and sulfation in the liver and is taken up into the tissues via extraneuronal catecholamine uptake mechanisms. Unlike other catecholamines, it lacks arrhythmogenic potential. Fenoldopam Fenoldopam mesylate is a dopamine DA1 receptor agonist that causes systemic and renal arteriolar vasodilation. It increases renal blood flow at doses of 0.05-0.1  µg/kg/min and reduces BP at 0.1-0.3  µg/kg/min. Phosphodiesterase inhibitors Phosphodiesterase inhibitors act by preventing the breakdown of cAMP, thereby prolonging its physiological response. They do not act via ÃŽ ²-AR stimulation. Their addition to a catecholamine has a synergistic effect in increasing inotropy. They also produce vasodilation and are termed ‘inodilators’. They improve myocardial diastolic relaxation (positive lusitropic effect) and augment coronary perfusion. The clinically used phosphodiesterase inhibitors include amrinone, milrinone and enoximone. Amrinone Amrinone is a bipyridine derivative. It provides positive inotropy and decreases SVR. The decrease in SVR is apparent immediately after administration, whereas positive inotropy is appreciable after 10-15 minutes. They are particularly useful in heart failure by increasing forward flow. It is administered as a bolus loading dose (0.5-1.5 mg/kg) followed by infusion (5-20  µg/kg/min). The potential side effects are thrombocytopenia (2-3%), gastrointestinal upset, myalgia, fever, hepatic dysfunction, ventricular arrhythmias and allergy. Milrinone Milrinone is a derivative of amrinone and is 20 times more potent. It does not cause fever or thrombocytopenia. It is administered as a bolus loading dose (50  µg/kg over 10 minutes) followed by infusion (0.375-0.75  µg/kg/min). Enoximone Enoximone is an imidazole derivative that has more pronounced vasodilatory effect than inotropic effect. It is administered as a bolus loading dose (0.5-1 mg/kg) followed by infusion (5-10  µg/kg/min). Levosimendan Levosimendan is a new inotropic agent belonging to the class of calcium-sensitizing agents, i.e., it sensitizes the myocardium to the actions of calcium. It has vasodilating and anti-ischemic properties mediated by opening of K+-ATP channels. The haemodynamic effects include increase in SV and CO and reduction in filling pressures, mean arterial pressure (MAP), mean pulmonary artery pressure (MPAP) and SVR. It also promotes lusitropy. It is useful in patients with compromised left ventricular function, difficulty in weaning from CPB and right ventricular failure. It is used in a loading dose of 12  µg/kg over 10 minutes followed by an infusion of 0.1  µg/kg/min. Calcium chloride Calcium ions play an important role in excitation-contraction coupling in the cardiac myofibrils. It has positive inotropic effect that is effective after CPB and in the short-term treatment of myocardial pump failure. The rise in BP occurs secondary to increased inotropy and vasoconstriction. However, it can attenuate the ÃŽ ²-AR effects of epinephrine in the postoperative cardiac surgical patients. It is administered in the dose of 2-4 mg/kg every 10 minutes. Calcium Gluconate the clinically available compound of calcium ,contains less than half of ionized calcium and has to be metabolized in the liver before action. VASODILATORS Vasodilators cause relaxation of arterial smooth muscle thereby reducing SVR and MAP. In addition, they also have venodilating property. They aid discontinuation of CPB by decreasing preload, right and left ventricular afterload, improving lusitropy and CBF. They are useful in the perioperative treatment of systemic and pulmonary hypertension, myocardial ischemia and ventricular dysfunction complicated by excessive pressure or volume overload. Sodium nitroprusside Sodium nitroprusside (SNP) acts by acting as a substrate for the formation of nitric oxide (NO) in the vascular endothelium. Binding of NO to its receptor induces a conformational change in the enzyme guanylate cyclase and production of cGMP from GTP. cGMP is the second messenger that eventually leads to vascular smooth muscle relaxation via numerous intermediate steps. SNP predominantly causes arterial and arteriolar vasodilation, but at high doses venodilation also occurs. Reflex tachycardia is apparent with its administration. SV and CO are increased only if the preload is maintained with intravenous fluids. SNP has a potential to cause ‘coronary steal’ phenomenon in patients with coronary artery disease as the epicardial coronary arteries also dilate diverting blood away from the stenosed endocardial coronary arteries. It decreases pulmonary vascular resistance (PVR) and MPAP. It abolishes hypoxic pulmonary vasoconstriction and may contribute to hypoxia. The infusion rate is 0.5  µg/kg/min, and titrated to effect. It is reconstituted in a dextrose-containing solution. SNP is sensitive to light, therefore the infusion syringe and tubing are wrapped with opaque material to prevent light induced structural breakdown of the drug. Cyanide toxicity may occur with the use of SNP above 1.5 mg/kg acute dose or 8  µg/kg/min chronic infusion. SNP is used during hypothermic CPB to promote uniform cooling by preventing cold induced vasoconstriction, to reduce the perfusion pressure, to reduce afterload by decreasing SVR and to increase pulmonary blood flow by decreasing PVR. Nitroglycerin Nitroglycerin (NTG) acts by the same mechanism as other nitrates. NTG is primarily a venodilator and reduces ventricular preload and myocardial oxygen consumption. NTG is of particular importance in patients with congestive heart failure as it unloads the left ventricle. It has modest effects on SVR and BP. It reduces PVR. The starting dose of intravenous nitroglycerin is 0.5  µg/kg/min which may be titrated to effect. Attention must be paid to the fluid status as CO may drastically reduce. At higher doses systemic vascular dilation occurs. NTG is helpful in coronary artery disease because it causes epicardial coronary artery dilation. It is metabolized in the liver. Methemoglobinemia occurs at high infusion rates. Intravenous nitroglycerin has a half-life of 1-3 minutes. Tolerance develops when administered for more than 8 hours. Nitric oxide Nitric oxide (NO) is the endothelium derived relaxing factor. Its mechanism of action has been described above. It has a very short half-life of 5 seconds. Inhaled NO promotes pulmonary vascular dilation. It can be used upto 80 parts per million (ppm) in patients with severe right ventricular failure and pulmonary arterial hypertension. As inhaled NO is rapidly taken up by the heme group of guanylate cyclase, it only acts locally in the pulmonary vascular bed causing pulmonary vasodilation. It has no systemic effects. Phenoxybenzamine Phenoxybenzamine is a non-competitive ÃŽ ±1 and ÃŽ ±2-AR blocker. It decreases PVR and SVR, thereby increasing CO. It is used to promote vasodilation during deep hypothermic circulatory arrest for uniform cooling and for the treatment of pulmonary hypertension. Phenoxybenzamine is a very potent and long acting vasodilator. It was traditionally used for afterload reduction, pulmonary vasodilatation, and in adrenal tumors such as pheochromocytoma. Phentolamine, a shorter acting agent is now more commonly used. VASOPRESSORS Vasopressors act on arteries and arterioles to increase SVR (ÃŽ ±-AR effect). They have some ÃŽ ² –AR effect also. Catecholamines such as norepinephrine, and epinephrine and dopamine at high concentrations are potent vasoconstrictors. In addition, sympathomimetics such as phenylephrine, methoxamine, ephedrine, metaraminol and mephentermine are also vasoconstrictors. They are metabolized by COMT and MAO. Phenylephrine Phenylephrine is a pure ÃŽ ±1-AR agonist and its primary action is to increase SVR. Reflex bradycardia may be seen. Vasoconstriction of renal, splanchnic and other vascular beds occurs. Coronary perfusion pressure is increased due to increase in diastolic pressure. The intravenous bolus dose is 50-100  µg and infusion rate is 0.5-1.0  µg/kg/min. Its effect is apparent in 1 minute and lasts upto 20 minutes. It is commonly used to increase SVR and therefore the perfusion pressure on CPB. Mephentermine Mephentermine has direct action on ÃŽ ±-AR and ÃŽ ²-AR, and indirect action by releasing norepinephrine at the nerve terminal. It increases CO and SVR. Its acts immediately on intravenous injection and it’s action lasts 30 minutes. It is used in 15-45 mg bolus doses and as 0.1% infusion titrated to effect. Vasopressin Vasopressin,a hormone of the anterior pituitary is a potent vasoconstrictor. It mediates vasoconstriction by inhibiting K+ ATP channels on vascular smooth muscles and blunting the rise in cGMP (due to NO and ANP) and cAMP (due to ÃŽ ²2-AR stimulation). It is one of the modalities of treating vasodilatory shock after CPB. It is used in the infusion dose of 0.01-0.1 U/min for this purpose. At higher doses it has the potential to cause renal and splanchnic vasoconstriction. It is also administered as a bolus dose of 40 U i.v. during cardiopulmonary resuscitation. Suggested reading Hoffman TM. Newerinotropesin pediatric heart failure. J Cardiovasc Pharmacol. 2011 Aug;58(2):121-5 Rognoni A, Lupi A, Lazzero M, Bongo AS, Rognoni G. Levosimendan: from basic science to clinical trials. Recent Pat Cardiovasc Drug Discov. 2011 Jan;6(1):9-15. Tavares M, Rezlan E, Vostroknoutova I, Khouadja H, Mebazaa A. New pharmacologic therapies for acute heart failure. Crit Care Med. 2008 Jan;36(1 Suppl):S112-20. Petersen JW, Felker GM. Inotropesin the management of acute heart failure. Crit Care Med. 2008 Jan;36(1 Suppl):S106-11 Ward RM, Lugo RA Cardiovascular drugs for the newborn.Clin Perinatol. 2005 Dec;32(4):979-97 Hug CC Jr. Making a choice ofinotropesandvasodilatorsin clinical situations.J Card Surg. 1990 Sep;5(3 Suppl):272-7 Stanford GG. Use of inotropicagentsin critical illness. Surg Clin North Am. 1991 Aug; 71(4):683-98.

Impact of Prison on Fyodor Dostoevskys Poor Folk, The Double, and The Idiot :: Dostoevsky Poor Folk Essays

Impact of Prison on Fyodor Dostoevsky's Poor Folk, The Double, and The Idiot Fyodor Mikhailovich Dostoevsky is perhaps one of the most well known but least understood authors from the nineteenth century. His life was one full of misfortune and suffering; his works filled with religious pondering and philosophical discussions. Dostoevsky's life experiences were integrated into the characters in his pieces, both in terms of personality and ideology. An especially important turning point in his life was his arrest and imprisonment at the age of twenty-seven, shortly after the beginning of his writing career. This prison sentence and time in exile served to shape his perceptions and beliefs towards life, which were then incorporated into his literary works. Dostoevsky entered the Chief Engineering Academy in Saint Petersburg in 1838, at the age of 17. Upon his graduation, he served in the civil service, but gave it up to pursue writing full-time. 1846 saw the publishing of his first books, Poor Folk, and The Double. In Poor Folk, he explores some of the social issues of the day, and the work has even been dubbed of a "socialist character." During this time, he had joined forces with other young intellectuals, and began attending meetings headed by Petrashevsky. These young "social realists" would meet and discuss current political issues -- most importantly, the idea of the liberation of the serfs. This issue was especially of interest to Fyodor, who had been exposed to the cruelties of serfdom early in his life. He had a deep hatred of the institution of serfdom, which was perhaps rooted in his guilt towards the murder of his father. It was thought that Mikhail Andreevich was murdered by his own serfs during a particularly violent bout of anger towards them. Fyodor, while he was in no way associated with the death (he was in school in Saint Petersburg at the time), none the less felt guilt. Part of this may have been due to his incessant nagging for more money from his father during his last few years. This group of idealists was influenced by the changing political status in Europe during the middle of the nineteenth century. This was a time of a new social awareness -- new rights and liberties were being fought for and won, governments were transforming, and a series of "utopian socialist" books were quickly becoming popular. Dostoevsky had been an avid reader of such authors as Hugo, Sand, Sue, and others in this field.

Carmina Burana

A work that many have, at least heard a piece, of is Carmina Burana. Carl Orff composed this piece of music in 1936. A German, he was one of few composers that continued work during the Anti-Semitic rule of the country. Orff based his work off of a collection of poems found at the monastery of Benedikbeuren that dates back to the Twelfth Century! Carmina Burana is a set of twenty-five pieces that concern many of things going in everyone’s life today.Drinking, gambling, love, sex, fate, and fortune are just a few of the topics Orff composed of. 1 In this concert report I will go through the pieces that stood out the most to me. As mentioned, the most famous piece of this work is the opening sequence, â€Å"O Fortuna†. This glamorous piece begins with the full orchestra and chorus playing a loud, brave tone that quickly drops off into, what I hear as a loud whisper, sung by the entire chorus. Orff doesn’t let the listener take a break by coming back with same loud tone that the piece began with.Percussion instruments can be vividly heard throughout this opening piece, seemingly above the rest of the instruments. Early in this work, Orff establishes his theme of a â€Å"Wheel of Fortune†. 2 With the boldness of the opening sounds I feel that Orff is setting the tone for the whole work. Although the work is sung entirely in Latin, the translation of the first movement may surprise most people. The opening words â€Å"O Fortune† gives the listener an idea what the piece is about. As the piece goes, Orff describes fortune as oppressing and poor, in what I believe he was feeling at the time.The last words of this movement, in translation â€Å" everyone weep with me â€Å" were the biggest surprise to me because the orchestra ends the piece in carnival like melody. The second movement of Orff’s work is titled â€Å"Fortune plango vulneraâ€Å". This is personally my favorite piece of the work because of the hit or miss har mony. Different instruments take turns using the high-low rhythms, along with the chorus. The male voice is prominent at the beginning but soon after you can hear the voice of the full orchestra. Before reading the text n translation, this piece gave the idea of a rabbit jumping through to pasture or meadow to a novice listener like myself. This piece picks up from the last movement still pertaining to fortune. In the latter part of this piece Orff actually wrote in his overall theme by mentioning â€Å"the wheel of Fortune turns†. The fourth movement, â€Å"Omnia sol temperat† is sung in a completely different way. It begins with a male soloist singing, accompanied softly by violins. The way Orff chose to display this movement shows that there is no defined rhythm he is following.The soloist singing in a profound masculine voice sets the tone for this movement. The next movement discussed stands out as being one of the longest works of the cantata. â€Å"In taberna q uando sumus† opens with stringed instruments followed by percussion, and then a variety of other instruments join with the chorus. â€Å"When we are in the tavern†, the title sets this piece up for what I think would have a been a popular movement when it originated. Orff tells of drinking and gambling at the tavern, then goes on to list thirty names such as â€Å"the rich man† and â€Å"the poor man† that all drink.This stood out to me because I didn’t see this coming at all! It is also my least my favorite piece of the work. With the setting what it is, I didn’t particularly like the minor tone heard on and off in this movement. Orff could have been trying to relay a message by this of the tavern as a sometimes dark, bad place. The last movement of the cantata, â€Å"O Fortuna† begins just as the piece began with the same instruments and harmony. The last movement mirrors the first in a way that makes the listener understand the true tone of this work.I compliment Orff for doing this because I feel it is necessary. With a piece as strong and bold as this, I would think most composers would have chose to do this. After going back and re-listening to the first and last piece, there is no difference to my ear. The last movement does not lack any of the strength of the first movement; it’s a repeat that is well deserved. This theme has been used in many American movies, but sadly it is seldom recognized. Carl Orff made his mark in music history with Carmina Burana, namely the first and last movements â€Å"O Fortuna†.There are many more movements in this piece that all have uniqueness and glamour. Even though I am not the most avid Carl Orff fan, this piece surprised me with every movement. The overall performance of this piece was outstanding, with all the different melodies and tones, the use of full orchestra to solo vocalist, and an excellent job of conducting by Jeffery Thomas, I can see how this piece gained as much fame as it did. 1 â€Å" The Enjoyment of Music† Eleventh Edition, Kristine Forney and Joseph Machlis 2 http://classicalmusic. about. com/od/20thcenturymusic/a/carmina_burana. htm

Imaginations, Values, and Emotions

Imaginations, Values, and Emotions There are wide variations in regard to time periods and genres as far as art works are concerned. It is worth noting that some art works were founded on individuals’ minds or cultural and social influences.Advertising We will write a custom essay sample on Imaginations, Values, and Emotions specifically for you for only $16.05 $11/page Learn More In addition, other art works were as a result of an influence from the features and styles used during previous periods and were a reaction or continuation to the artistic styles. The link between the renaissance and neoclassical art eras will be examined. There will be an analysis and discussion of whether there was a reaction to or continuation between the two art periods. Renaissance, characteristics, and social conditions that led to the advent The word renaissance is a French term. It came up during the nineteenth century and elaborates the rebirth of a period that occurred between the fourteenth and sev enteenth century. The artists during this period emulated the works of art from artists before this period. In addition, they incorporated color and light via novel dimensions. During this period, there was innovation of the sense of space and perspective that allowed viewers to view in 3- dimensions. Art was fundamentally inspired by sacred and commissions motivations (Rachels Rachels, 2007). Some of the notorious artists during the renaissance art period included Raphael, Leornardo, and Michelangelo. The art works done during this period were elaborated in that they included more than the vanishing point, horizontal line, and linear perspective. The artists during the renaissance art period had a keen interest in the way light hit objects and consequently formed shadows (Rachels Rachels, 2007). The light and shadows played a great role in attracting viewers to particular areas on the object. The artists also wanted the viewer to get involved emotionally as he looked at the objec t and, therefore, get encouragement and faith. The artists also invested greatly in naturalism and realism. For instance, they wanted images of people to appear more realistic. The images were solid and showed real emotions. This made the viewer to start thinking about what the people were feeling or thinking. Neoclassical, characteristics, and social conditions that led to the advent Neoclassical art refers to a form of art that was exceptionally unemotional and severe. Its rigidity was closely associated with the Baraque and Rocco styles. It was as a result of the renewed interest arising from the classical period. This was greatly beneficial to a number of revolutions. Romanticism emerged in the 1800s as a reaction to neoclassicism and some of the famous artists during this period included Robert Adam, Bertel Thorvaldsen, and Anton Rapheal Mengs.Advertising Looking for essay on art and design? Let's see if we can help you! Get your first paper with 15% OFF Learn M ore The key characteristics of the art works during the neoclassical period included stern heroism, lack of emotions, and seriousness. The artists often used sombre colors and brilliant highlights that portrayed self- sacrifice and self- denial. The neoclassical period had distinct features of the structure and form used during the classical art period. In addition, there was clarity and realism (Rachels Rachels, 2007). It is worth noting that similar to the renaissance period that had connections to the social situations and political structure, the neoclassical period had a direct connection to the political events. Neoclassism was linked to the French Revolution beliefs. Similarities and differences between neoclassical and renaissance art periods Whereas the artists during the neoclassical period aimed at recreating the classical art period, which was the Romans’ and Greeks’ style, the renaissance period was basically a rebirth. During the renaissance peri od, people started considering science as a way of answering questions and receiving information. Previously, only religion was used. The neoclassicists were in search of a simple way of thinking that was not chaotic. Continuation of the previous historical art period During the neoclassical period, artists wanted to bring about advancements as was the case during the neoclassical period (Rachels Rachels, 2007). During the two periods, there were great advancements in visual arts, music, painting, and architecture. In addition, the fame associated with artists during the renaissance period continued during the neoclassical period as a result of the artistic philosophies and ideologies experienced. Specific works During the renaissance period, Michelangelo came up with a masterpiece referred to as David. In addition, the Psyche Revised by Cupid’s Kiss was created by Antonio Canova. The renaissance art was represented by David through an impression of the political scenario th at prevailed. On the other hand, the Psyche Revised by Cupid’s Kiss was a depiction of the artist’s concentration on the classical arts and Romans (Rachels Rachels, 2007). Relationship between the works The two works of art discussed reflect huge artistic developments. Irrespective of the fact that the two periods were a representation of great advancing periods as far as art was concerned, the artists and art purposed on extremely varying things. During the renaissance period, artists focused on the political systems, social situations, and culture. The art was created from the social conditions that contributed to the political system in Europe. Hence, it is evident that the link between neoclassical and renaissance cannot be underrated.Advertising We will write a custom essay sample on Imaginations, Values, and Emotions specifically for you for only $16.05 $11/page Learn More References Rachels, J. Rachels, S. (2007). The elements of mora l philosophy (5th ed.). New York: McGraw-Hill.

What is the effect of mass on friction Essay Example

What is the effect of mass on friction Essay Example What is the effect of mass on friction Essay What is the effect of mass on friction Essay To conduct this experiment, certain materials will be required. These include the following: 2 force meters (one that measures forces up to 5 Newtons and one that measures forces up to 10 Newtons), a mass i.e. a block of wood of about 15cm3, a table or any smooth surface, a strip of slightly grainy sandpaper and another strip of more grainy sandpaper. The experiment will be set up as shown below (fig 1).Fig 2This experiment was set up into two sections, firstly the effect of mass on dynamic friction and then the effect of mass on static friction.Dynamic Friction: For the dynamic friction experiment, the force of friction will be read off the force meter. This is due to Newtons second law stating that Fnet = ma. When the block is being pulled along at constant speed, the acceleration is 0 so Fnet = 0. Therefore P = F and so the force shown on the force meter is equal to the frictional force.A hook should first be placed into the block of wood so that it may be pulled along by the forc e meter. Then the block must be massed and its mass recorded (see table of results) along with its weight (for this experiment 100g = 1N). The mass is then placed onto the first surface and the force meter hooked onto it. Refer to the pilot test to know which force meter would be more suitable at this stage. The block is then pulled along the surface at constant speed and the reading on the force meter should be recorded in the table of results. Repeat this reading two or three times to increase its reliability and then calculate an average of all the readings. Remember to include the repeat readings and the average in your table of results. The experiment should then be set up again using the same block of wood and the same surface but by adding a mass onto the block thus increasing its weight. The new mass and weight of the block should also be recorded in the table of results. The block is then pulled along at constant speed by the force meter and its reading recorded along with the repeat readings. Repeat this about 7 times, each time adding an extra mass on ( the mass being added on should be the same each time).This whole procedure must then be repeated on each surface using the same block of wood, the same surfaces and materials and the same intervals of masses to ensure fair testing. For each experiment there should only be one variable that changes: the mass, all others should be controlled and kept constant.Static Friction: This experiment is set up in the exact same way, keeping the same variables and materials. This time, the block should not be pulled along the surface at constant speed but the force meter should be pulled gently until the block moves. The reading must be taken just as the block moves. This should be repeated as in the dynamic friction experiment and the same masses should be added. All readings should be recorded in a separate table.Now that the experiment is prepared, a pilot test can be carried out. In this pilot test the range of readings will be chosen along with which surfaces to choose from. Our range of masses was chosen to be from 0 1 kg with 8 readings on each of the three surfaces. A choice of five surfaces was offered and the three chosen were the ones that differentiated the most from each other. Very grainy sandpaper was supplied but during the pilot test it was found that as it the grains were so large, the lighter masses would just glide right over them.Friction is a force that tries to oppose motion. It is caused when two surfaces are in contact, by the roughness of the materials rubbing against each other, deformations in the materials, and a molecular attraction between materials. If looked through a microscope, friction on the molecular level is due to the unevenness of the surfaces. The two surfaces would have bumps, hills and valleys that would interfere with the sliding motion. If mass was to be added to these surfaces, the bumps and valleys would be pushed harder together, locking th em tighter together making it harder to move them. This means that as more masses are added onto the block, the reading on the force meter will go up proportionally. Therefore if we plot a graph of the force on the force meter over the weight, a straight line through the origin should be obtained.

Teens Can Make The Choice! essays

Teens Can Make The Choice! essays Teens Can Make The Choice! Teenagers who get pregnant unintentionally have the choice of keeping their baby or having an abortion. Some choose to keep the child if they are able to support it, but some do not realize that they are not able to give all the support that they need. According to the Journal of the American Medical Association, every day in the United States, about 3,000 teen-age girls will learn that they are pregnant (Rowland). Abortion is not illegal for teenagers to go get it done themselves. Abortion law should stay the same, because there are teenagers that are not able to support another living being, and they should be able to have an abortion. The idea of abortion for young teenagers should be allowed, if they have difficulties raising the child. There are many contraceptives that are available for protection, why are they not used? The According to the Journal of the American Medical Association from 1985 to 1990 birth rates rose about 18 percent among the age of 15-19 year olds, and 95 percent of those were unintended (Rowland). The Planned Parenthood is a voluntary reproductive health care organization that women choose their own destines in when or whether to have a child. They offer many contraceptives such as birth control, condoms, and guidance to any woman. The agencies such as the Planned Parenthood are such great agencies that are available for women to take advantage so that they can have a better life. Abortion being legal is a great advantage because there are many young teens that are not ready to give birth to another living being and take care of it. The law gives a teenager the right to get an abortion without the parents consent. If the law is giving teenagers to have an abortion legally then why are they not using the advantage? According to Peggy Sparks of the Birmingham Community Education says; that they are looking for love, support, and other things t...

The ouster of Vikram Pandit, and what that means for big banks Research Paper

The ouster of Vikram Pandit, and what that means for big banks - Research Paper Example This paper will address Pandit’s ouster, and describe how this major event in Citigroup will influence the future operations of Citibank, as well as other banks in the same industry. Mr. Pandit took over as the bank’s CEO in 2007 when the bank was in a financial turmoil, but slightly recovered the profitability of the bank in 2010. Under Pandit’s management, much of Citi’s resources were devoted for future profitability. Expanding market to the developing countries was a prospective Pandit held (David, Suzanne, and Dan 1-2). The reasons offered for Pandit’s ouster emanate from struggles to recover from past financial crises at the bank. Mr. Pandit was forced to resign after the board of Directors at Citi bank felt that he managed the bank poorly. The board also claimed lack of appropriate communication from the CEO on vital business matters. During the tenure of Pandit, the shares of Citigroup fell by 89%, which resulted in a revolt by shareholders over his executive pay. The Federal Reserve also rejected Citigroup’s plan to purchase back stock. In addition, there was a $2.9 million write-down by Morgan Stanley, of a brokerage joint venture. All these unfortunate happenings can be numerically represented, but most probably point to poor judgment, rather than day-to-day oversight of specific business units (David 2). Michael Corbat, Pandit’s replacement, may not perform as Pandit, who was credited a well performer, who knew the positions of the bank inside out. Corbat’s strategic directions for future of the company are also still uncertain. Many challenges Corbat, as he will feel the pressure of impressing quickly, since the bank’s shareholders are now frustrated about the bank’s uncertainty. Citigroup investment bank is a potential victim of shrinkage. It is enormous, but with uneven revenue since the times of the financial crisis. This continued decline has to be addressed in order to gain stability again. Mr. Corbat will also have to deal with the â€Å"black box† reputation of the bank. Observations show that the bank’s disclosures are not as comprehensive as those of other banks are. In order to regain the confidence of investors, Corbat has to tackle this issue also. Consumers should expect to feel the difference between Citi managed by Pandit, and Citi managed by Michael Corbat, Pandit’s successor. This kind of transition at Citi may not positively influence on the financial health of the US banking industry, and the general US economy. This is because Citi is a bank that has been considered ‘important’ by the regulators, amid financial crisis. It is a troubled bank, and still struggles to gain stability. Pandit was a CEO that had set out to turn around the case of Citi bank, and ensure its total economic recovery. However, by firing such a dedicated CEO, Citi bank risks continued vulnerability to financial crises. The shareholde rs of Citi bank continue to be adversely affected by the bank’s prolonged stagnation in financial instability. However, more parties will feel the pinch of this as it will affect the whole banking industry as well as the national economy. Citi is in the process of repairing its balance sheet, it is then expected that it will cut down on customer lending, in a bid to save more. Its customers will not access

Fundamental Principles of Accounting Essay Example | Topics and Well Written Essays - 250 words

Fundamental Principles of Accounting - Essay Example Principles of accounting dictate that for losses to be incurred, institutions do not meet the breakeven point. The breakeven point ensures a company to pay all the bills while ensuring the business continues running (Wagner & Dittmar, 2006). Financial analysis is also important in the scenario presented by the two cases. Forecasting is clear in the two cases and both companies had a strategy placed on the set objectives. Agents of accounting such as profits, losses, liabilities, expenditure, and other financial statements come in handy in ensuring the success of the set objectives. The ability to access the stability, viability, and the profitability of a company is evident in both cases. The role of decision making in financial assessment is also evident in both cases. This is because it dictates the continuity or discontinuity of the operational department of a business. The cases display proper ability to make purchases of given materials while providing consumers with products. In the long run, the company benefits from the profits, solvency, stability and liquidity of assets (Wagner & Dittmar,

What is the effect of oil prices change on stock market of GCC Assignment

What is the effect of oil prices change on stock market of GCC countries - Assignment Example Of the seven countries, Qatar is the most sensitive to changes in oil prices and often responds in a quicker manner as compared to the others. The main objective of this paper is to discuss the effects of oil price changes on the Stock market of GCC countries. Over the last three decades, the drop in oil prices in the second half of 2014 qualifies as a noteworthy occurrence as compared to other episodes within that time. Between 1984 and 2013, there were five major declines in oil prices (Arouri, 2010). Notably, there were 30 percent or more price decreases within a period of six months. These declines in oil prices coincided with significant changes in oil markets and the global economy including; the increase in oil supplies and change in the OPEC policy, U.S recession, Asian crisis and the worldwide financial crisis of 1986, 1990, 1997 and 2007 respectively (Arouri, 2010). Interestingly, the latest episode of collapse in oil prices bears remarkable parallels with the1985-86 collapse. Saudi Arabia amended its policy in December 1985 leading to a 61 percent decline in the oil prices. Between January and July 1986, oil prices dropped from $24.68 to $9.62 per barrel and prevailed for more than a decade (Arouri, 2010). A repeat of this phenomenon was observed after the steep decline in oil prices intensified in the second half of 2014 following a policy alteration by Saudi Arabia in November 2013. Cumulatively, the decline in oil prices, from the peak that was experienced in 2011, became larger than that experienced in non-oil commodity prices. With this regard, oil prices affect the major economic variables of Oil producing countries, as well as, the stock returns of these involved countries (Arouri, 2010). The GCC is comprised of six countries including Qatar, Kuwait, Saudi Arabia, Kuwait, Bahrain and the United Arab Emirates. In 2007, these countries possessed about 47 % of oil reserves, produced 20% of oil in the

Simulation Analysis Essay Example | Topics and Well Written Essays - 1000 words

Simulation Analysis - Essay Example Since Quasar is the sole participant in the marketplace they have just created for themselves a monopoly market structure. The first three rounds of the simulation discuss strategic decision during the first three years of operation. In 2003 the company needs to determine the optimum price for the product. As the CEO of the company I have a team of executive that is going to help me along in the process. My team is composed of four members in three functional areas: marketing, finance, technology, and outside marketing consultant. Keeping the lines of communication open among a team of businesspeople is essential in order to manage an operation in an efficient manner (Kotler, 2002). The decision I made was to set the price of the Neutron computer at $2,550. At this price the volume of sales was 5.3 million units and the net profit of the company is $1.29 billion. If I increase the price from the optimum price point volume decreases as well as profits. On the hand if I decrease the price from my optimum price point of $2,550 volume increases a bit but profit go down. My primary objective was to find the best mix that optimizes the profitability of the company. The second round of the simulation takes me to year 2004. The company I’m running is a monopoly player. In a monopoly the firm has control price, but it is not immune to the law of supply and demand (Varian, 2003). The demand curve is downward sloping which means at higher prices the demand of the product decreases. Two of my executive Robert (marketing vice-president) and Janet (Finance vice-president) have different perspective on how to achieve greater growth. The issue was the marketing budget and whether an increase or decrease from the 2003 $400 million budget would affect the demand for the product. Janet suggested a low figure of $100- 200 million in marketing expenses. It seemed as if she was thinking like an accountant or

Default Determination Term Paper Example | Topics and Well Written Essays - 1000 words

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Psychic Bisexuality Essay Example | Topics and Well Written Essays - 1500 words

Psychic Bisexuality - Essay Example He insisted that nothing about sex could be understood without taking an account of " universal bisexuality of human beings" (1950 179). Psychoneuroses analysis gave him the confirmation of the "postulated existence of an innate bisexual disposition in man" (1908 165-166). For Freud the concept of bisexuality "embarrasses all our enquiries into the subject and makes them harder to describe" (1940a 188). The concept of bisexuality by Freud were based on the understanding that "all human beings are capable of making a homosexual object-choice" (Freud, 1905,) fn p. 56), "Bisexuality is a possibility" (Smith) in many cases due to varies reasons. Biological sources gave birth to Freud's theory of bisexuality. Freud explains the boy's wish to be with father as mother during oedipal complex and the untimely sense of phallic activity during pre-oedipal stage, which is a part of their biological disposition. The basic of psychoanalysis is masochism, refined by Freud. He introduced three kinds of masochism, and feminine masochism, "an expression of the feminine being nature" (p. 161) is required here. It is when an individual inflicts and receives pain during sex and situations like, "being castrated, or copulated with, or giving birth to a baby" (p. 162) are crucial to masochism. Women's beating fantasies also urged Freud to produce the theory of "feminine masochism." Freud was very complicated when it came to gender discussions. He also linked this theory with passivity and called it a "biological fact." He continued that, "Passivity is not a whole of masochism." But it is a major part of it. Men are considered active and passivity is a women's thing. He initiated "feminine" and "moral" factors as secondary masochism. Basically what I gather from his thinking is that passivity is owned by women and that is why her capability of masochism gives her the power to love selflessly as a wome n and mother. He also considered it as a part of the sexual pleasure which is intense. According to Freud a crucial point he insisted on is that mutation during development may also result in masochism. What is feminine maturity and why is it more complicated then masculine maturity Similar yet so different tasks are taken by boys and girls on the way to maturity. This path to maturity constitute of the pre-oedipal, oedipal and post oedipal period. Freud said that "variations in the chronological order and in the linking up of these [pre to post oedipal] events are bound to have a very important bearing on the development of the individual". (Freud 1931 p.79). Freud clarifies the focus of Psychoanalysis in his essay feminity by Freud, "sets about inquiring how she comes into being, how a woman develops out of a child with a bisexual disposition." And he further says, "Undoubtedly, the material is different to start with in boys and girls: the difference in the structure of the genitals is accompanied by other bodily differences". Freud insisted that the sexual development of a girl into a woman is far more complicated than that of a boy. And "it includes two extra tasks to which there is nothing corresponding in the development of a man." He explains, "she must find a way to give up

Simulation Analysis Essay Example | Topics and Well Written Essays - 1000 words

Simulation Analysis - Essay Example Since Quasar is the sole participant in the marketplace they have just created for themselves a monopoly market structure. The first three rounds of the simulation discuss strategic decision during the first three years of operation. In 2003 the company needs to determine the optimum price for the product. As the CEO of the company I have a team of executive that is going to help me along in the process. My team is composed of four members in three functional areas: marketing, finance, technology, and outside marketing consultant. Keeping the lines of communication open among a team of businesspeople is essential in order to manage an operation in an efficient manner (Kotler, 2002). The decision I made was to set the price of the Neutron computer at $2,550. At this price the volume of sales was 5.3 million units and the net profit of the company is $1.29 billion. If I increase the price from the optimum price point volume decreases as well as profits. On the hand if I decrease the price from my optimum price point of $2,550 volume increases a bit but profit go down. My primary objective was to find the best mix that optimizes the profitability of the company. The second round of the simulation takes me to year 2004. The company I’m running is a monopoly player. In a monopoly the firm has control price, but it is not immune to the law of supply and demand (Varian, 2003). The demand curve is downward sloping which means at higher prices the demand of the product decreases. Two of my executive Robert (marketing vice-president) and Janet (Finance vice-president) have different perspective on how to achieve greater growth. The issue was the marketing budget and whether an increase or decrease from the 2003 $400 million budget would affect the demand for the product. Janet suggested a low figure of $100- 200 million in marketing expenses. It seemed as if she was thinking like an accountant or

Psychic Bisexuality Essay Example | Topics and Well Written Essays - 1500 words

Psychic Bisexuality - Essay Example He insisted that nothing about sex could be understood without taking an account of " universal bisexuality of human beings" (1950 179). Psychoneuroses analysis gave him the confirmation of the "postulated existence of an innate bisexual disposition in man" (1908 165-166). For Freud the concept of bisexuality "embarrasses all our enquiries into the subject and makes them harder to describe" (1940a 188). The concept of bisexuality by Freud were based on the understanding that "all human beings are capable of making a homosexual object-choice" (Freud, 1905,) fn p. 56), "Bisexuality is a possibility" (Smith) in many cases due to varies reasons. Biological sources gave birth to Freud's theory of bisexuality. Freud explains the boy's wish to be with father as mother during oedipal complex and the untimely sense of phallic activity during pre-oedipal stage, which is a part of their biological disposition. The basic of psychoanalysis is masochism, refined by Freud. He introduced three kinds of masochism, and feminine masochism, "an expression of the feminine being nature" (p. 161) is required here. It is when an individual inflicts and receives pain during sex and situations like, "being castrated, or copulated with, or giving birth to a baby" (p. 162) are crucial to masochism. Women's beating fantasies also urged Freud to produce the theory of "feminine masochism." Freud was very complicated when it came to gender discussions. He also linked this theory with passivity and called it a "biological fact." He continued that, "Passivity is not a whole of masochism." But it is a major part of it. Men are considered active and passivity is a women's thing. He initiated "feminine" and "moral" factors as secondary masochism. Basically what I gather from his thinking is that passivity is owned by women and that is why her capability of masochism gives her the power to love selflessly as a wome n and mother. He also considered it as a part of the sexual pleasure which is intense. According to Freud a crucial point he insisted on is that mutation during development may also result in masochism. What is feminine maturity and why is it more complicated then masculine maturity Similar yet so different tasks are taken by boys and girls on the way to maturity. This path to maturity constitute of the pre-oedipal, oedipal and post oedipal period. Freud said that "variations in the chronological order and in the linking up of these [pre to post oedipal] events are bound to have a very important bearing on the development of the individual". (Freud 1931 p.79). Freud clarifies the focus of Psychoanalysis in his essay feminity by Freud, "sets about inquiring how she comes into being, how a woman develops out of a child with a bisexual disposition." And he further says, "Undoubtedly, the material is different to start with in boys and girls: the difference in the structure of the genitals is accompanied by other bodily differences". Freud insisted that the sexual development of a girl into a woman is far more complicated than that of a boy. And "it includes two extra tasks to which there is nothing corresponding in the development of a man." He explains, "she must find a way to give up

Irish Family Law Essay Example for Free

Irish Family Law Essay Discuss some of the key provisions and principles of the United Nations Convention on the Rights of the child. Include an example of Irish law or police that complies /does not comply with the States obligations under the convention. Introduction This essay will look at some of the key provisions of the United Nations Convention on the Rights of the Child (UNCRC) and discuss Ireland’s progress in fulfilling their obligation under the UNCRC. The author will reflect briefly on the history of children’s rights in Ireland. The essay will consider what measures the state has taken to develop strategies and policies to improve the wellbeing of the children. Recent government initiatives will be explored will be explored to assess whether the UN Convention has been implemented into National Policy. The author will also consider the legal framework to gauge if Irish legislation as it stands today complies with the states obligations under the convention. Historical Perspective Attitudes towards children and their rights have changed dramatically in recent years; these changes have been slow to come about. Historically children were deemed the property of their parents and had no rights. In the late 1800’s, events abroad began to have an impact on attitudes if Ireland. The 1908 children’s act Britain and Ireland remained the main piece of legislation safeguarding children’s rights for almost one hundred years until the Irish Child Care Act 1991. The United Nations was set up in 1945 after the Second World War to promote peace and human rights. In 1989, it was decided that children needed a separate set of rights to ensure that children worldwide were nurtured, protected and allowed to enjoy childhood. In 1990, Ireland signed the United Nations Convention on the Rights of the Child and ratified it in September 1992 thereby committing the state to implementing the UNCRC. The UNCRC is based on four core principles, the best interest of the child, the right to life survival and development, respect for the views of the child and non-discrimination. Article 3.1 of UNCRC states ‘In all actions concerning children, whether undertaken by public or private social welfare institutions, courts of law, administrative authorities or legislative bodies the best interest of the child shall be a primary consideration’. Legislation The Child Care Act 1991 is the legislative framework in Ireland for promoting the welfare of the child. This legislation deals primarily with the protection of children in emergencies, or in care. The Childcare Act 1991 Part II, places a statutory onus the HSE to promote the welfare of children in need of care and protection. The 1991 Act also gave the HSE more power to provide childcare and family support services and while doing so must have regard to the following: ‘It is generally in the best interest of the child to be brought up in his or her own family. Having regard to the rights and duties of the parents, the welfare of the child is the first and paramount consideration and that as far as is practicable, the wishes of the child should be considered† (Childcare Act 1991). Part II of The childcare act implements the principle of the best interest of the child in law. The wording in part II of the childcare act would also appear to comply with Article 5 of the UNCRC requiring that ‘Governments respect the right of parents of provide for and care for their children’. Under the Irish Constitution, which is the fundamental law of the land, the family is based on the institution of marriage; only married parents have automatic rights to guardianship of their children. The rights of unmarried parents, in particular fathers are not considered under Irish law, consequently the rights of their children are being contravened. This is in contradiction with Article 18 of the UNCRC, which requires ‘State parties to recognise that both parties have equal responsibility for the care and development of their children. Article 7.1 states that the child †¦has the right to know and be cared for by his or her parents†, while Article 9 requires â€Å"state parties to ensure that a child will not be separated from his parents against the ir will†¦Ã¢â‚¬  UNCRC (1989). Irish law makes it impossible for many children to realise these rights. In the case of unmarried parents, only the mother has automatic right to guardianship. The father must have the consent of the mother or pursue his rights to guardianship through the courts. Article 41 and 42 of the Constitution provides protection for the family unit based on marriage; it does not give individual rights and is more about protecting the institution of marriage than the family. The children of unmarried parents are not afforded the same protection under Article 41 and 42. Under the Irish Constitution as it currently stands, Ireland is not compliant with the UN convention. The constitution, in many cases, denies children of unmarried parents the right to be cared for by both parents. Article 3 .3 of the UN Convention calls for all ‘services and facilities responsible for the care and protection of children to conform to the standards established by competent authorities’. UNCRC (1989) . In 2006 The Child Care (Pre-School Services) Regulations 1996 were revised and replaced by the Child Care (pre-school Services) (No 2) Regulations. The 2006 regulations are more child centred and focus on the health, welfare and development of the child. These regulations are the regulatory framework within which all-early years services must operate in Ireland. Through a vigorous system of inspection, compliance with the pre-school regulations is monitored by the HSE to ensure that all Early Years services meet the minimum standards required by law. The Child Care (Pre School Services) Regulations implement the UN Convention in Irish Law. National Policy Since Ireland ratified the UN Convention in 1992 there have been numerous changes in policy, showing the Irish Government’s commitment to implementing the UNCRC. In 1999, Children First National Guidelines for the Protection and Welfare of children was published by the Department of Health and Children. These guidelines highlight the importance of child welfare and are intended to provide a framework for all those who care for and work with children. Children First is based on the key principle that the best interest s of the child is paramount. These guidelines implement the best interest of the child and Article 19 of the UN Convention into National Policy. In 2006, the Committee on The Rights of The Child (CRC) recommended that Ireland review the Children First guidelines and consider putting them on a statutory basis CRC (2006). The guidelines were revised in 2011 to include new policy, legislation and organisation. at the time of the launch of the new guidelines in 2011, the government announced its intention to put the Children First Guidelines on statutory footing, it will then a legal requirement to report concerns regarding a threat a child’s welfare Nuig (2012). In 1997, the Irish Government made a commitment that a National Childcare Strategy would be developed and an expert working group on Childcare was charged with developing that strategy. Despite Ireland’s commitment to the UN Convention, prior to this there was no national policy on children. The National Children’s Strategy 2000-2010 set three National Goals: to listen to children, think more about what children need and act for children in a holistic sense National Children’s Strategy Our Children-Their Lives (2000). Finally, Ireland was moving towards implementing the UN Convention into National Policy. For the first time children were asked about what they thought they needed and what they would like see happen for them in the future in Ireland. This fulfilled the states obligation under Article 12 of the UN Convention, which requires that ‘State Parties shall assure to the child who is capable of forming his or her own view the right to express those views freely in all matters affecting the child, the views of the child being given due weight in accordance with the age and maturity of the child’ UNCRC (1989). Two thousand five hundred children were involved in these consultations; their responses identified a need for more play and recreation opportunities National Children’s Strategy (2000). In response to these consultations and to honour the states commitment to the UN Convention Article 31 which requires state parties ‘to recognise the right of the child to rest and leisure, to engage in play and recreational activities appropriate to the age of the child’ the government launched Ready, Steady, Play! A National Play Policy in 2004. The objectives of the National Play Policy were to give children a voice, to raise awareness of the importance of play and to improve and maximise the quality and safety of play areas particularly in disadvantaged areas National Play Policy (2004-2008). In 2009 Sà ­olta, the National Quality Framework and Aistear the Early Childhood Curriculum Framework were rolled out. Sà ­olta looks at quality provision and underpins the child’s right to have a voice, recommending that ‘each child has opportunities to make choices, is enabled to make decisions and has his /her choices and decisions respected’ CECDE (1999). Aistear promotes partnerships with parents and play NCCA (2009). Together with Regulation 5 of the Child Care (Pre School Services) (No.2) Regulations 2006 Sà ­olta and Aistear use the Whole Child Perspective to ensure the holistic development of the child while implementing the UN Convention into practice on a daily basis. It is evident that the Irish State is committed to implementing the UN Convention into Irish Law. The legislation introduced in recent years goes some way towards implementing children’s rights into law. In this authors opinion the main obstruction to Ireland’s compliance under the convention is the Irish constitution in its present form. All legislation is subject to the Constitution; therefore, any legislation introduced around child protection or welfare must be compatible with the Constitution. In 2006, the Committee on the rights of the child recommended that Ireland ‘takes further action to incorporate the Convention into domestic law’ CRC (2006). It is this author’s opinion that changes will have to be made to the constitution to separate the rights of the child from those of the family. Many of the policies such as The National Childcare Strategy, The National Play Policy and Children First all underpin the right of the child as outlined in UN Convention. However these policies take the form of guidelines or frameworks, they are not part of the legislation. Following the recommendations of the CRC (2006), it is hoped that the Children First Guidelines will be put on a statutory footing ensuring mandatory reporting of child neglect and abuse. This would help safeguard future generations of Irish children from neglect and abuse. Reference List †¢Centre for Early Childhood Development and Education (2006) Sà ­olta The National framework for Quality in Early Childhood Care and Education. Dublin: Centre for Early Childhood Development and Education. †¢Child Care Act 1991 †¢Department of Children and Youth Affairs (2011) Children First: National Guidelines for the Protection and Welfare of Children, Government Publication: Dublin Available at: http://WWW.dcya.gov.ie/documents/child_welfare_protection/children First.pdf †¢Ireland, Government of (1937) Bunreacht Na hÉireann, Constitution of Ireland. Dublin: Stationery Office. †¢Ireland, Government of (2000) National children’s Strategy, Dublin: The Stationery Office. †¢Ireland, Government of (2006) Child Care Pre-School Services NO 2 Regulations 2006 and child Care Pre-School Services No 2 Amendment Regulations 2006. Dublin: The Stationary Office. †¢National Council for Curriculum and Assessment, (2004) Aistear the Early Childhood Curriculum Framework. Dublin: National Council for Curriculum and Assessment. †¢National Play Policy (2004) Ready Steady Play! [Online]. Available at: http/www.dcya.gov.ie/documents/publications (Accessed 20 January 2012). †¢Nui Galway (2011) Quality Awareness in Early Learning, Galway: Nui Galway. †¢Nui Galway (2012) The Child and Family in Irish Law, Galway: Nui Galway. †¢UN committee on the rights of the Child (CRC) (2006) UN Committee on the Rights of the Child: Concluding Observations, Ireland, 29 September 2006, [Online] Available at: http:www.childrensrights.ie/resourcse.un-com (Accessed: 14 January 2012. †¢United Nations (1989) Convention of the Rights of the Child [Online].Available at: http//wwwcirp.org/library/ethics/UN-Convention/(Accessed: 17 January 2011)

ERP And Network At Dabur Essay

ERP And Network At Dabur Essay Dabur is a Indian consumer goods company with interests in Oral Care, Hair Care, Skin Care, Health Care, Home Care and even in foods. From its humble first phase in the bylanes of Calcutta in the year 1884 as an Ayurvedic medicines company. Dabur has come a stretched way today to become among the top companies. Dabur India Limited is the 4th largest FMCG Company in India. Dabur had a turnover of approximately Rs. 3390.9 Crore FY 09-10 Market Capitalisation of over Rs 15500 Crore which clearly shows the companys stand. The company has kept an eye on new generations of customers with a variety of products that provide to a modern lifestyle, while supervision not to estrange past generations of faithful customers. Daburs network is in the form of star topology with 6 DAMA (Demand Assigned Multiple Access) links from Hughes Escorts Communications Limited (HECL). There are approximately 40-50 Time Division Multiple Access (TDMA) VSATs (Very Small Aperture Terminals), which will be used for linking the distribution network. Then there is Virtual Private Network (VPN) connectivity involving Daburs offices at various places like Delhi and Mumbai, moreover the corporate office. This link will soon be un-mitigated to other locations, also.The choice of the network depends upon location and feasibility runs on multiple media. The company uses IDSN connectivity as a support for its prime connectivity. Astonishingly, contrary to the current trend, Dabur doesnt have various leased lines to hold up its datacom network. The Situation: Problem Faced By The Company Before ERP Implementation For many years, Dabur had been using Fox Pro based systems for its handling logistics but as the network has grown the distribution pressure rises technology development was necessary. Fox Pro was a database in which each of the department likes sales, finance etc had a separate database for their respective departments. It was not a relational database. The company faced a lot of problem because this like data inconsistencies etc. It become necessary to integrate the fragmented distribution network for the benefit of the company. This was the time when Dabur felt the need to implement some kind of ERP system. ERP Implementation in 4 stages till now 1st ERP implementation Baan Dabur implemented Baans ERP system in 1999 for automation of the manufacturing process. This was the first ERP system which was implemented by the company in the major plants at Sahibabad and Baddi respectively. The server used for this was Alpha Unix servers and this was situated at the commercial office are used for Baan and around 200 concurrent users can login from in cooperation with plants using PAMA VSATs and fibre in the distant Baddi plant. In Baan ERP system the key modules includes finance, manufacturing,master production planning, intelligent resource planning,dealer planning and costing. The various modules keep the track of the material as the inventory moves through the plant and they are synchronised to each other. The primary distribution plan becomes a very important component of the manufacturing system. The planning process of the compnay includes one months stable Rolling Production Plan (RPP) of the company and two months rolling plan later on, based on a Rollin g Sales Forecast (RSF) of Dabur. Problem in case of Baan The operation of the manufacturing system has been very difficult as raw materials for Daburs products are mostly sourced from the various unorganised sectors where fruits and herbs and other natural recourses are procured. The other challenge was of extensive customisation which was necessary to meet stringent FDA regulations in the quality circle in Pharma product lines. Not only this, BaaN requires a central server which was also a problem for the company. As with the majority companies, sales at Dabur crest in the last 4-5 days of the particular month which leads to more load on the server. If the company dabur in this case,depends on this sort of central server architecture, which would be associated through VSATs, the network would be extremely overburden during each and every month-end. However, Dabur never required making the network a serious component in the automation of the outbound logistics. The company determined to go for an ERP answer which was Network Independent and it found that MFG/PRO could be run on independent servers at every location it was a good choice that suited its unique needs. 2nd ERP implementation MFG/PRO ERP Dabur therefore initiated automation of the outward logistics system in April, 2001 by means of its primary circulation system named Project Synergy, which involves the execution of the MFG/PRO ERP system. The MGF/PRO system was running in greater than a dozen Carrying and Forwarding Agents (CFAs) and the major warehouses all over the country. It had covered more than 90 sites in the main Distribution will be finished by 2002. Implementation Once it was decided that MFG/PRO it will be to lever the outbound logistics then a core implementation team was made which includes end users from dissimilar departments, like IT, sales, distribution and planning, finance and was set up in order to work. The deployment was made in four stages. In the first stage a requirement study was done here a model was developed. Dabur has many other strategic business units each one of it is having a different need in terms of outbound logistics. It is a traditional FMCG company into family units and healthcare products, pharmaceutical products, food products, which is a perishable products division, ayurvedic products for both the medicine and home segments. All these divisions have diverse requirements. The heart team had its job to cut out plus it had to develop a ordinary business model, which could supply to each and every segment at the identical time. Significant benefits were visible in locations where the ERP system had been implemented. These include: Improvement occur in sales dispatches to the carrying and forward agents (CFA). The sales earlier were greatly overloaded with 80 percent of sales taking place in the last week of the month which led to a number of trouble such as cheque bouncing and sales returns from pushed sales to meet sales targets. Improvement was seen in collections process also. Collections have recorded an improvement of about 6 days after implementing ERP and now are more evenly spread more than the month which leads to substantial savings on working capital protected up in out-bound logistics. Reduction in unsold stock inventory nad sales returns. Stocks in carrying and forwading agents are noticeable to fundamental distribution planners in commercial and un-saleable categories most important to better distribution nad management. fundamental management of sales schemes. The corporate office manages the schemes and free issues and the ERP system keeps a tough test on schemes most important to decline in misuse of schemes in the field. Reasons: why the shifted to another ERP system (SAP) By 2005 Dabur felt the need of maintaining two independent ERP systems for the company. They were facing some of the issues like there were still data redundancies and inconsistencies in the database system. Substantial amount of rework was essential in just data format translation between the two systems. It still did not provide a holistic image and thus posed troubles in formulating a policy or taking business significant decisions. Maintenance cost of MGF/PRO was also very high. Dabur realized that it is not just the operational excellence it needed but in also needed decision support infrastructure and as a result of this the proposal of a solitary organization wide ERP implementation was planned in Dabur. So, with the help of Accenture, Dabur implemented strategic and operational changes by implementation of organization wide SAP core modules. 3RD ERP implementation SAP (major change) Migrated from standalone Enterprise Resourse Planning systems which includes Baan and Mfg to centralized SAP ERP system from 1st April, 2006 for all the business units of dabur. Dabur implemented a country wide new Wide Area Network infrastructure for running centralized Enterprise resourse planning system and setting up of new data center at KCO head office in Ghaziabad. Addition of system to the distributors for capturing Secondary Sales Data information to collect near real-time pipeline information was done by 2004. Dabur decided to turn round out the IT services to the latest plants in the country. Dabur is no immunity with respect to other industries and realized it needed to execute enhanced and quickly and make more rapid decisions in order to outpace its upper class in revenue and prosperity growth. Accenture projected infront of dabur that Dabur to improve its supply chain management, to meet such goals and sales and distribution capabilities should also be improved and use IT as a strategic enabler for its business strategy. This incorporated migration to a nimbler outsourcing model that would create significance through quickness and sustain business initiatives and safeguarding of its SAP ERP system. SAP basically, was selected due to the extensive experience in India and it is used by its competitors also. How Accenture helped Dabur Accenture proposed that Dabur improve its sales and distribution services and supply chain management capabilities and use information technology as a tactical enabler for its business strategy. From an IT standpoint, Accenture suggested a two-pronged strategy to Dabur that includes resettlement to a nimbler outsourcing model that would create value through nimbleness and hold up business initiatives and protection of its SAP enterprise resource planning system. Accenture assembled a group of extremely trained industry experts so that it can bring these initiatives to life, as well as some professionals who have widespread SAP design and implementation experience in this field which was an important factor. It implemented a new sales and distribution strategy and in this Accenture helped in developing a widespread strategy that was noticeable as Daburs first significant endeavour to identify key customer segments in urban and rural markets, customize sales programs for key accounts and reorganize Daburs sales teams by one of four trade channels. There was some profit from these initiatives like increase in annual sales by 17% whereas amplify in profits by over 40% performance more operational effectiveness and cutting down of costs. Operational Benefits Impact Lost Sales -40% Forecast Error -53% Full, on time delivers +7% Rolling production plan adherence +73% Accenture supported this business approach with a lucrative IT solution. It has developed in-house over several platforms, which captured actionable information crosswise the national footprint of practically 500 distributors. In the area like that of product distribution, the desired team focused on bolstering the efficiencies and rural market diffusion and designed a channel-specific strategy for chemist , modern trade, wholesalers and convenience stores. In just the beginning of a supplementary efficient sales program, Accenture paid special consideration to how Dabur might recover service to Indian extra-large retailers, which are likely to account for an additional 15 percent of consumer product sales by 2010. For this group of customers, the group recognized a totally new operating model that includes a pricing architecture framework to aid negotiations and revised role and odd jobs for each and every one members of the trade field force. In devising this strategy, the Accenture and Dabur team optimized the companys distribution processes and internal logistics for mega retail customers, and put incentives in set to drive definite goals such as uniformity of sales in grocery stores, increased sales via wholesale channels. 4th ERP implementation SAP APO (Current Scenario) Automating forecasting: Dabur hence decided to automate the procedure to develop its forecasting procedure. The company was already running SAP ERP from 2006 and decided to put into practice SAPs Advanced Planner and Optimizer (APO).To guarantee the precision of SAP APO, chronological data was deconstructed to originate the baseline sales and impact of ATL/BTL inputs. Dabur has to a great extent gets benefits from SAP APO with enhanced business outcomes. Project was divided into four different phases. The first phase was Diagnosis in which design and organisation structure was done. It also established the potential opportunity size and the business case. In the second phase the design of the supply chain took place. The third phase the actual implementation of APO modules took place. In the last phase the actuall running took place (April 2010). Once you have input the growth target the entire sales volume plan will be generated. All the other calculations are in real time like required capacity planning, markets where we can get more business. The ERP system will then convert the sales which was forecasted into the real/actual sales at factory level. Changes experienced in top line, bottom line and inventory turnover due to ERP implementation Before the deployment, the lost sales which were earlier accounted to 6% were decreased to 3.75%. More-over the companys error forecast was also reduced from 85 to 40 percent and its forecast accuracy amplified from 25 to over 60 percent. Achieving this act in less than eight months was a enormous success for Dabur. This would not have been possible exclusive of a business benefit-led move towards to the exercise moderately than an IT-led approach. With the recent execution of ERP, the effectiveness of the distribution and logistics network is expected to advance more in the future. Consumer health division grew by 12.5%, that division has been impacted in the first quarter by the ERP platform changeover. Future Challenges Forward integration of SAP with distributors and stockists is a big challenge. Implementation of SAP HR and payroll has to be done. Along with this backward integration os SAP suppliers. Conclusion The implementation of ERP system in a consumer goods company is an enormous complex undertaking, ERP system can effect every aspect of organizational functioning and design.ERP system lead to highly standardised and highly computerised information. A strong program management approach and an implementation partner having good business understanding and proven experience were other factors that served as catalysts.

Holocaust-concentration Camps Essay -- essays research papers

Concentration Camps   Ã‚  Ã‚  Ã‚  Ã‚  Concentration Camps were a big part of the Holocaust. My first topic is the concentration camp Dachau. Then I will talk about another concentration camp called Bergen-Belsen. After that, I will tell you about the concentration camp Treblinka. Finally, the last concentration I will talk about is Auschwitz-Birkenau. Describing these camps will inform you that concentration camps were a huge part of the Holocaust.   Ã‚  Ã‚  Ã‚  Ã‚  Dachau was a devastating concentration camp of the Holocaust. Dachau was built in 1933. At first, it was a extermination camp for Jewish people and political prisoners. Then it became a full-time concentration camp for prisoners. In 1943, the Nazis decided to force the occupants into back-breaking labor. The Nazis made the prisoners make arms and supplies for the war. At this camp, they performed brutal medical experiments on the prisoners. Over 3,500 people had experiments performed on them and most all died. When the war was coming to an end, the United States liberated over 32,000 prisoners on April 29, 1945. This was one of the most devastating concentration camps of the Holocaust.   Ã‚  Ã‚  Ã‚  Ã‚  Bergen-Belsen was another horrifying concentration camp. This camp was a holding center camp. This means that the people that were sent there were going to be kept there until they died, or until the war was over. The people at this camp were usually killed by diseases like tu... Holocaust-concentration Camps Essay -- essays research papers Concentration Camps   Ã‚  Ã‚  Ã‚  Ã‚  Concentration Camps were a big part of the Holocaust. My first topic is the concentration camp Dachau. Then I will talk about another concentration camp called Bergen-Belsen. After that, I will tell you about the concentration camp Treblinka. Finally, the last concentration I will talk about is Auschwitz-Birkenau. Describing these camps will inform you that concentration camps were a huge part of the Holocaust.   Ã‚  Ã‚  Ã‚  Ã‚  Dachau was a devastating concentration camp of the Holocaust. Dachau was built in 1933. At first, it was a extermination camp for Jewish people and political prisoners. Then it became a full-time concentration camp for prisoners. In 1943, the Nazis decided to force the occupants into back-breaking labor. The Nazis made the prisoners make arms and supplies for the war. At this camp, they performed brutal medical experiments on the prisoners. Over 3,500 people had experiments performed on them and most all died. When the war was coming to an end, the United States liberated over 32,000 prisoners on April 29, 1945. This was one of the most devastating concentration camps of the Holocaust.   Ã‚  Ã‚  Ã‚  Ã‚  Bergen-Belsen was another horrifying concentration camp. This camp was a holding center camp. This means that the people that were sent there were going to be kept there until they died, or until the war was over. The people at this camp were usually killed by diseases like tu...

Tuberculosis :: essays research papers fc

Tuberculosis TB is a disease that can cause a serious illness and can damage a person's organs. Every year more than 25,000 people in the U.S. are diagnosed with TB disease. That's only a fraction of the amount of people who carry the Mycobacterium tuberculosis. Mycobacterium tuberculosis is a rod-shaped bacterium. TB is spread through the air by carriers of the germ. People who breathe the same air can become infected with the TB germ. People who do work around or with people with the TB disease should take medicine. TB infection means that the person has the TB germs but they are in an inactive state. When TB germs enter the body, the immune system builds a wall around them. While TB germs are inactive, they cannot cause any damage. These germs can stay alive for many years in these walls and eventually break out. At this time TB is active then it becomes TB disease. It can now affect the system's organs. A person can have TB disease shortly after being infected with TB germs if the person's immune system is weak. TB can attack any part of the system. The lungs are the most common area of attack. People with the TB disease have one or more of the following symptoms: a cough that hangs on, fevers, weight loss, night sweats, constant fatigue, and loss of appetite. A person with the TB disease in the late stages will cough up blood streaked sputum. People who have Active TB disease usually only have mild symptoms. There are three tests to diagnose TB disease. One is the Tuberculin Mantoux PPD skin test; two is a Chest X-ray which is given after the Skin test is positive; three Sputum Test reveals if TB germs are in thick liquid a person coughs up. The Tuberculin Mantoux PPD skin test is given by placing a substance called PPD Tuberculin under the top layer of the skin with a very small needle and syringe. The doctor will inject the needle into the skin which will only feel like a slight pen prick. A few days later the skin test reaction will be read by a trained health worker. If the skin around the prick israised and it is bigger or the same size as a pencil eraser then the person is likely to have been infected with TB germs. This does not mean he or she has TB disease. You should always retest yourself even if the first test was negative for a few reasons. If your immune system has been weakened, then your immune system may